It’s a very powerful anti-inflammatory substance that may help fight numerous diseases. SummaryĬurcumin is the biologically active agent in turmeric. These supplements are widely available in health stores and online. Nevertheless, curcumin is poorly absorbed, so it’s best to get a supplement that also contains piperine/bioperine, which has been shown to enhance its absorption by 2,000% ( 22). In fact, the results of this study found that curcumin performed as well as the antidepressant drug prozac ( 21). It’s a powerful antioxidant, can improve heart health, and may help prevent cancer ( 18, 19, 20).Īccording to one study, curcumin may also help fight depression. It’s so effective that it has been compared to anti-inflammatory drugs in some studies - without any major side effects ( 15, 16).įor example, in a study in 45 people with rheumatoid arthritis, 500 mg of curcumin per day was more effective than the anti-inflammatory drug diclofenac ( 17).Ĭurcumin also has numerous other health benefits. Turmeric contains curcumin, a powerful substance that has been studied thoroughly in recent years ( 12).Ĭurcumin fights inflammation at the molecular level by blocking an inflammatory signalling molecule called NF-kB ( 13, 14). It has been used as a medicinal herb in India for thousands of years. Turmeric is a popular spice known for giving curry its yellow color. If you want to give berberine a try, you can find it in health stores and online. It lowers triglyceride and blood pressure levels, as well as total and LDL (bad) cholesterol, which may reduce your risk of heart disease ( 1, 6, 7, 8).īerberine has also been shown to have antibacterial effects and may protect against heart failure ( 9, 10, 11). In a study in 116 people with type 2 diabetes, the substance reduced fasting blood sugar levels by 20% and HbA1c (a marker for long-term blood sugar levels) by 12% ( 5).īerberine is also very effective at improving other health markers. Studies show that taking berberine can lower blood sugar levels to a similar extent as the popular diabetes drug metformin ( 4). In particular, berberine is believed to reduce glucose production in your liver and improve insulin sensitivity ( 2, 3). These effects are thought to be due to numerous mechanisms. It provides various health benefits but is particularly effective at lowering blood sugar levels ( 1). It isn’t well known but may be one of the most powerful supplements on Earth. Berberine is a bioactive substance extracted from certain plants.
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